• Lancashire Clinical Trials Unit (CTU)

The Lancashire Clinical Trials Unit (CTU) has been set up to manage health related trials for UCLan and external organisations. The Lancashire CTU team has accrued many years of experience in the skills required to develop, manage and analyse clinical trials with a growing specialisation in trials of complex interventions, in particular feasibility trials. The formulation of the Lancashire CTU structure was initiated in 2012 and we are currently supporting national and international trials.

The Lancashire CTU offers a quality assured service for the coordination and delivery of key services pertaining to robust clinical trials of complex interventions and other well designed studies.

We offer support in:

  • Trial design and developing collaborative applications to funders
  • Trial and site set-up and on-going management, including oversight monitoring
  • Randomisation
  • Data management (including form (CRF) design, data entry and data cleaning)
  • Statistical analysis and reporting

These services are underpinned by our robust quality assurance processes

We specialise in complex intervention trials in the topic areas of:

  • Stroke
  • Midwifery
  • Cancer
  • Musculoskeletal health
  • Public/population health
  • Mental health

Lancashire Clinical Trials Unit group photo


If you are interested in engaging with the Lancashire Clinical Trials Unit then please apply for our support using the Lancashire CTU request form as early as possible. The completed form should be emailed to lancashirectu@uclan.ac.uk

 

Expertise and Subject Areas

  • Trial design and development
  • Feasibility trials
  • Complex intervention trials
  • Trial management
  • Data management
  • Statistics
  • Trial Reporting
  • Research
  • Quality Assurance

 

Publications

2019

Ouyang M, Boaden E, Arima H, Lavados PM, Billot L, Hackett ML, Olavarría VV, Muñoz-Venturelli P, Song L, Rogers K, Middleton S, Pontes-Neto OM, Lee T-H, Watkins C, Robinson T, Anderson CS, for the HeadPoST Investigators (2019) Dysphagia screening and risks of pneumonia and adverse outcomes after acute stroke: an international multicentre study. International Journal of Stroke, doi.org/10.1177/1747493019858778

The effectiveness and cost-effectiveness of strength and balance Exergames to reduce falls risk for people aged 55 years and older in UK assisted living facilities: a multi-centre, cluster randomised controlled trial (2019) Stanmore EK, Mavroeidi A, de Jong LD, Skelton DA, Sutton CJ, Benedetto V, Munford LA, Meekes W, Bell V & Todd C. BMC Medicine, 17; 49

Minhas JS,  Wang X, Lavados PM, Moullaali TJ, Arima H, Billot L, Hackett ML, Olavarria VV, Middleton S, Pontes-Neto O, Asita De Silva H, Lee TH, Pandian JD, Mead GE, Watkins C, Chalmers J, Anderson CS, Robinson TG & on behalf of the HeadPoST investigators (2019) Blood pressure variability and outcome in acute ischemic and hemorrhagic stroke: a post hoc analysis of the HeadPoST study. Journal of Human Hypertension ISSN 0950-9240

Thomas LH, Coupe J, Cross L, Tan AL and Watkins CL (2019) Interventions for treating urinary incontinence after stroke in adults. Cochrane Database of Systematic Reviews, Issue 2. Art. No.: CD004462. DOI: 10.1002/14651858.CD004462.pub4.

2018

Holland EJ, Watkins CL, Boaden E and Lightbody CE (2018) Fidelity to a motivational interviewing intervention for those with post-stroke aphasia: A small scale feasibility study. Topics in Stroke Rehabilitation 25 (1). pp. 54-60. ISSN 1074-9357

Gibson JME, Thomas LH, Harrison JJ, Watkins CL (2018) Stroke survivors’ and carers’ experiences of a systematic voiding programme to treat urinary incontinence after stroke. Journal of Clinical Nursing, 27(9-10):2041-2051. doi: 10.1111/jocn.14346 http://clok.uclan.ac.uk/21881/

Patel K, Watkins CL, Sutton CJ, Holland E-J, Benedetto V, Auton, MF, Barer D, Chatterjee K, Lightbody CE (2018) Motivational interviewing for low mood and adjustment early after stroke: a feasibility randomised trial. Pilot and Feasibility Studies, 4:152. doi: 10.1186/s40814-018-0343-z http://clok.uclan.ac.uk/24218/

Radford, Kate, Sutton, Chris J, Sach, Tracey, Holmes, Jain, Watkins, Caroline Leigh, Forshaw, Denise, Jones, Trevor, Hoffman, Karen O’Connor, Rory et al (2018) Early, specialist vocational rehabilitation to facilitate return to work after traumatic brain injury: the FRESH feasibility RCT. Health Technology Assessment, 22 (33). pp. 1-156. ISSN 1366-5278

 

Events and News

2019

  • Lancashire CTU staff development day, University of Central Lancashire (June 2019)
  • Lancashire CTU stand at University Hospitals Morecambe Bay Trust (UHMBT) R&D conference (June 2019)
  • Lancashire CTU invited speaker: Clinical Research Network meeting (March 2019)
  • Lancashire CTU invited speaker: Clinical Research Network meeting (April 2019)
  • NW Coast Stroke Research Nurses meeting, Liverpool. Invited presentations on ICONSII, CONVINCE and COMMITS (May 2019)
  • Lancashire CTU staff attendance at Driving Interprofessional Collaboration – NIHR Statistics Group Third Annual Conference (June 2019)

2018

  • Lancashire CTU staff development day, University of Central Lancashire (June 2018)
  • Lancashire CTU stand at UK Stroke Forum (December 2018)
  • Oral presentations and posters by Lancashire CTU staff at UK Stroke Forum (December 2018)
  • Lancashire CTU stand at LTHTR research day (November 2018)
  • Oral presentations and workshop sessions at International Conference on The Essentials of Stroke Care, India (November 2018)
  • The Faculty of Health and Wellbeing hosted a Royal Statistical Society seminar on Knowledge Elicitation (December 2018) organised by CTU Statisticians
  • Lancashire CTU was represented at the NW Stroke Conference (June 2018)

Members

Directors

Prof Dame Caroline Watkins (Director)
Dr Gordon Prescott (Associate Director)

Trial Management

Denise Forshaw (Principal Clinical Trials Manager)
Shakil Patel (Clinical Trials Manager)
Emma Neil (Associate Clinical Trials Manager)
John Heney (Associate Clinical Trials Manager)
Anthony Anyon (Associate Clinical Trials Manager)
Alexandra Haig (Senior Clinical Trials Assistant)
Ruksana Isaji (Senior Clinical Trials Assistant)
Alison Gibbon (Trials Assistant)

Trial Design and Statistical Analysis

Svetlana Tishkovskaya (Lecturer in Health Statistics)
Naseerah Akooji (Senior Statistical Research Assistant)
Dr Miland Joshi (Lecturer in Health Statistics)
Chris Brown (Statistical Research Assistant)
Mollie Payne (Statistical Research Assistant)
Anna France (Statistical Research Associate)

Information Systems and Data Management

Joe Robinson (Senior Information Systems Developer)
Glenn Holt (Senior Clinical IS Assistant)
Alison Hadley (Data Co-ordinator)
Carole Bruce (Data Co-ordinator)
Moira Wilkinson (Clinical Trials Clerical Assistant)
Molly Cronshaw (Trials Clerical Assistant)

 

Quality Assurance

George Georgiou (Quality Assurance and Training Manager)

Administration

Dr Hayley Tyrer (Business Manager) 

Helen Oates
Helen joined the Lancashire Clinical Trials Unit in February 2018 as Assistant Business Manager. Helen has worked at UCLan for over 11 years primarily in Finance supporting the Faculty of Health and Wellbeing, School of Nursing and School of Community Health and Midwifery

Projects

Current projects

Completed Projects