Molecular Biophysics

Jeremiah Horrocks Institute (JHI)

The groups focus is on understanding structure function relationships of amphiphilic bioactive molecules and the design of new biomaterials.

The group is multidisciplinary and draws on a range of specialisms including, biology, (cell biology and microbiology), chemistry (biochemistry, synthetic chemistry), physics (biophysics, nano physics) and computational modelling to:

  • Investigate the mode of action of helical peptides and other bioactive amphiphilic molecules and to identify their molecular target(s)
  • Undertake structure-activity studies to improve the antimicrobial activity and oncolytic properties of amphiphilic, membrane interactive compounds
  • Develop computational methods for the identification and assessment of key functional characteristics of amphiphilic molecules with medical applications