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Dr Geraldine O'Connor

Senior Lecturer
School of Medicine
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Geraldine teaches Medicine, Physician Associate and Medical Science students with a focus on immunology and haematology subjects. She is Academic Lead for Year 1 of the MBBS (Medicine) programme as well as theme lead for Integrated Science and Clinical Medicine for Year 1 and Year 2 of the MBBS programme. She is also course leader for the BSc Medical Science. Her research activity is focused on molecular and cell biology projects within the human immune system.

Geraldine has published extensively in the area of human immune responses including studies exploring the genetic influences on the outcome of bone marrow transplantation (HLA, 2018), how HIV mutations impact immune recognition (Nature Structural & Molecular Biology, 2017), and how immune receptor expression can be used to identify malignant cells to aid diagnosis and prognosis in cancer (Archives of Dermatological Research, 2017).

While studying for a degree in Biochemistry in Trinity College Dublin Geraldine developed an avid interest in the human immune system and stayed on to do a PhD in Immunology within the School of Biochemistry and Immunology. After completion of her PhD she spent several years as a postdoctoral fellow at the National Cancer Institute within the NIH in the USA before moving as a research officer to the Department of Microbiology and Immunology at the University of Melbourne. Throughout her research career, she has worked on various aspects of the human immune system including research on human immunodeficiency (both genetic and acquired), and in understanding how differences between individuals impact their immune function and ultimately their health. She has supervised a range of undergraduate and post-graduate research students including MSc, MRes and PhD students. She has a particular interest in flow cytometer, and acts as laboratory manager for the flow cytometry facility at the University of Central Lancashire. In parallel with her research career, Geraldine has taught a wide range of students across scientific and healthcare disciplines including biological science, biomedical science, veterinary science, nursing, medicine, and physician associate students in the USA, Australia, Ireland, and the UK.

  • Postgraduate Certificate in Learning and Teaching in Higher Education, University of Chester, 2017
  • PhD Immunology, School of Biochemistry and Immunology, Trinity College Dublin, Ireland, 2007
  • BA (Mod) Biochemistry, with First Class Honours, Trinity College Dublin, Ireland, 2002
  • Immune responses
  • Natural Killer Cells
  • HLA biology
  • Cell signalling
  • Human genetic polymorphism
  • Member
  • Royal Society of Biology
  • British Society of Immunology
  • Reviewer
  • Journal of Biological Chemistry
  • Journal of Cell Transplantation
  • PLoS ONE
  • PNAS and Blood
  • Grant Reviewer
  • Arthritis UK
  • Medical Research Council (MRC)