Dr Bojlul Bahar
Senior Lecturer in Nutritional Sciences
School of Sport and Health Sciences
Bojlul is a Senior Lecturer in Nutritional Sciences within the Sport, Nutrition and Clinical Sciences team. Bojlul is a Molecular Nutritionist with a PhD in Nutrition & Food Science interested in inflammation and metabolic syndrome (obesity, type-2 diabetes/insulin resistance). Bojlul’s research focuses on regulating genes by dietary bioactive and identifying key signalling pathways involved in health and disease.
Bojlul is involved in the delivery of undergraduate BSc (Hons) Nutrition & Exercise Science and MSc Nutrition & Exercise Science programmes at the University of Central Lancashire. Bojlul has experience in MSc course leadership and curriculum development and works collaboratively with the Sport, Nutrition and Clinical Sciences team. He has a multidisciplinary background in applied biomedical research that positively influences his pedagogical approach to teaching. Bojlul has published 50+ peer-reviewed publications in food and health and supervised PhD and MSc research students.
Before joining the University of Central Lancashire, Bojlul was a UCD Research Fellow and a Senior Post-Doctoral Research Fellow at the Cell & Molecular Biology Laboratory of the Institute of Food & Health, University College Dublin. During the Post-Doctoral research, Bojlul’s research focused on the chronic inflammatory response associated with the metabolic syndrome and discovering novel bioactive compounds against those. Bojlul developed targeted transcriptome profiling technique to investigate the cause-and-effect relationship of bioactive and the molecular mode of action within the cells using a range of in-vitro, ex-vivo and in-vivo experimental models.
Bojlul completed PhD from the University College Dublin in 2006 as a Teagasc Walsh Fellow. In his doctoral research, Bojlul applied techniques of analytical chemistry (Isotope Ratio Mass Spectrometry) and functional genomics (Quantitative Gene Expression) to understand how the elements (Carbon, Nitrogen and Sulphur) from the diet get incorporated in mammalian tissues. His research demonstrated that gene transcriptome profile and stable isotope signature together provide valuable information about the production (organic or conventional, grass-fed versus grain-fed) and geographical origin of muscle meat. This information is useful for developing traceability of food from the plate to the farm.
- Postgraduate Certificate in Teaching and Learning, University College Dublin, 2016
- PhD Nutrition & Food Science, University College Dublin 2006
- MSc Agri. Biotechnology, Distinction with Award, Assam Agricultural University, India 2000
- BSc Agri. Genetics, First class Hons, Assam Agricultural University 1997
- Dr KC Bora Memorial Award, Assam Agri University, India 2000
- Metabolic inflammation and chronic diseases
- Plant-based diets for gut and immune health
- Registered Nutritionist (Nutritional Science)
- Fellowship of The Higher Education Academy
Bojlul has a research background in Molecular Nutrition and Immunology and he is currently pursuing research in the following areas Novel biomarkers for metabolic health The transition from a healthy state to a metabolic syndrome state is associated with a system-level shift in the cellular processes, ultimately leading to a loss of metabolic plasticity. Such a shift, when identified precisely, could be a critical checkpoint for intervention. Bojlul’s research involved developing and comparing gene transcriptional profiles from volunteers representing various metabolic syndrome stages through the application of advanced genomics and bioinformatics tools. Identification of biomarkers of metabolic health would lead to developing new diagnostic tool and effective management of metabolic syndromes. Regulation of mammalian sirtuin expression Sirtuins regulate cascades of genes, driving crucial intracellular processes (inflammasome activation, oxidative stress, circadian clock, ageing) leading to diseases. Hence, regulation of sirtuin expression serves as one of the earliest events that lead to the activation of a diverse range of downstream signalling pathways. Bojlul’s research involves the alternation of sirtuin expression by bioactive polyphenols and assessing its effect on intracellular processes associated with metabolic health and neurodegenerative (Alzheimer’s/dementia) disease models. The integrity of the intestinal gut epithelium The integrity of the gut epithelium is vital for our immune and metabolic health. Irreversible damage to the gut epithelium caused by microbial endotoxins, food additives, pharmacological excipients causes an unregulated entry of toxic compounds and harmful microorganism into the bloodstream. Bojlul has investigated the role of bacterial lipopolysaccharides and intracellular immune signalling pathways and developing nutritional strategies for preventing chronic inflammatory diseases such as inflammatory bowel disease and type-2 diabetes.
Use the links below to view their profiles:
- View their unique and persistent identifier on the ORCiD registry
- Full list of publications and articles on CLoK
- Google Scholar
- C4Global Research Group
- Research Centre for Applied Sport, Physical Activity and Performance
- Development of a transcriptome signature for the assessment of metabolic health of the South Asians living in the UK (applied for) Identifying genetic inflammatory markers in periodontitis as a guide to Alzheimer’s disease risk Identification of insulin resistance and resveratrol supplementation in overweight and obese adults Exploring the potential of anti-inflammatory bioactives from the medicinal plants of North East India for treatment of type-2-diabetes Marine functional food research consortium (NutraMara) Effect of dietary seaweed on the gut health and immunology of pig and humans Bovine neuropeptide Y and their receptors: potential role in the energy homeostasis
- Oral & Dental Research Trust Funding £5,000 (2019)
- School of Sport & Wellbeing £5,000 (2017)
- Department of Biotechnology, Govt. of India 8.5 million INR (2014)
- Marine Institute/Govt of Ireland, PhD funding € 75,000 (2012)
- Marine Institute, Ireland, Conference Presentation € 2,000 (2012)
- Teagasc Ireland, PhD funding € 63,000 (2009)
- CSIR, India, Junior Research Fellowship (2000-01)
- International Symposium on digestive physiology of pigs, USA 2012
- Agricultural Research Forum, Tullamore, Ireland 2011
- British Society of Animal Science & Agri Research Forum, Belfast 2010
- International Conference on Lactoferrin, structure, function and applications, France 2007
- European Federation of Animal Science conference, Dublin 2007
- International Symposium on Animal Functional Genomics, USA 2006
- International Congress of Meat Science & Technology, Dublin 2006
- International Food Conference, Dublin 2004
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