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Kamalinder K Singh

Prof. Kamalinder K Singh

Professor of Pharmaceutical Technology and Drug Delivery

School of Pharmacy and Biomedical Sciences

Maudland Building, MB031

+44 (0) 1772 89 5843

ksingh1@uclan.ac.uk

Subject Areas: Pharmacy and Pharmacology

Kamalinder leads the Nanomedicine and Innovative technologies research group at UCLan within the faculty of Clinical and Biomedical Sciences at University of Central Lancashire.  With more than 30 years experience in academia, her research interests are in the field of advanced drug delivery and drug targeting with focus on formulation design and development, and evaluation of different biocompatible nanoparticle-based platform technologies including protein, lipid and hybrid nanoparticles and exploiting them to deliver drugs across various biological barriers.

Full Profile

Kamalinder K Singh is Professor of Pharmaceutical Technology and Drug delivery at School of Pharmacy and Biomedical Sciences, University of Central Lancashire. After graduating from Panjab University, Chandigarh, Kamalinder joined SNDT Women’s University, Mumbai in 1984 as Lecturer in Pharmaceutics and subsequently promoted to Reader in 1993 and Professor of Pharmaceutics in 2001 and later held the position of Principal C. U Shah College of Pharmacy within SNDT Women’s University.

She has supervised over 20 Ph. D students and ongoing research programmes focus on nanoparticulate drug delivery systems including protein based nanoparticles, lipid nanostructures, nanosuspensions, lipospheres, microspheres, taste masking and nanophytopharmaceuticals and span the following areas of development; pre-formulation; formulation development; physicochemical assessment; stability assessment and prediction; in-vitro performance tests, transport; pharmacokinetics and bio-distribution and in vitro-in vivo correlation.  These drug delivery strategies are primarily being investigated for cancer, parasitic diseases and dermatological conditions either alone or in combination to prepare mixed nano-systems for delivery of single drug or co-delivery of multi-agents. She has particular research interest in development of nanocarrier systems for selective targeting to parasitized RBCs for effective treatment of malaria. She has a number of successful collaborations with other universities, and pharmaceutical industry leading to publications and development of new products and hold several patents in the pharmaceutical area.

Qualifications:

  • Ph.D Pharmaceutical Technology, SNDT Women’s University, Mumbai, India, 1993
  • M. Pharm in Pharmaceutics, Panjab University, Chandigarh, India, 1983
  • B. Pharm, Panjab University, Chandigarh, India, 1981

Research Groups:

  • Nanomedicine and Innovative technologies and Drug design, analysis and delivery research group

Publications

Khurana, Rajneet Kaur, Bansal, Arvind, Beg, Sarwar, Burrow, Andrea Julie, Katare, O. P, Singh, Kamalinder K and Singh, Bhupinder (2017) Enhancing Biopharmaceutical Attributes of Phospholipid Complex-loaded Nanostructured Lipidic Carriers of Mangiferin: Systematic Development, Characterization and Evaluation. International Journal of Pharmaceutics, 518 (1-2). pp. 289-306

Sidhaye, Aditi A, Bhuran, Kanchan C, Zambare, Sneha, Abubaker, Munna, Nirmalan, Niroshini and Singh, Kamalinder K (2016) Bio-inspired artemether-loaded human serum albumin nanoparticles for effective control of malaria-infected erythrocytes. Nanomedicine, 11, (21), pp 2809-2828.

Patil, Hemlata, Tiwari, Roshan, Repka, Michael A and Singh, Kamalinder K (2016) Formulation and development of orodispersible sustained release tablet of domperidone. Drug Development and Industrial Pharmacy, 42 (6). pp. 906-915.

Pople PV, Singh K K, (2013) Development and evaluation of colloidal modified nanolipid carrier: Application to topical delivery of tacrolimus, Part II - In vivo assessment, drug targeting, efficacy and safety in treatment of atopic dermatitis, Eur. J. Pharm. Biopharm., 84, 72–83


More Publications

 

 

Membership of professional and learned bodies

  • Controlled Release Society (CRS)
  • American Association Pharmaceutical Scientist (AAPS)
  • International Pharmaceutical Federation (FIP)
  • UK Ireland Chapter of Controlled release Society
  • Indian Chapter of Controlled release Society
  • Indian Pharmaceutical Association

Projects

  • Targeted nanoparticulate drug delivery system for the treatment of brain cancer (Industry funded)
  • Design and development of nanoparticles for selective targeting of antimalarial drug to plasmodium infected Red blood cells (pRBC)
  • Nanostructured lipid carriers and Nanomicelles for Breast cancer
  • Quality by design approach to formulation and optimization of Nanosuspensions of poorly water soluble drugs
  • Lipid nanocarriers for deeper skin layer targeting
  •  Microparticles for Taste masking

TEACHING activities and responsibilities

  • Teaches on the following Modules:
  • Advanced Drug delivery
  • Research Methods and Project Development
  • Research Skills
  • Pharmaceutical Technology and Formulation Development
  • Drug Design and Delivery
  • Cancer Management and Therapy
  • Practical Techniques in Industrial/Medicinal Chemistry

Research

Kamalinder has extensive research experience in the field of Pharmaceutical Nanoscience and nanoparticle design for drug delivery. One strand of her research focusses to address the problems of much neglected tropical disease Malaria where she has developed functionalized nanoparticulate drug delivery systems for selective targeting to parasitized RBCs (pRBC). Other research strands involve developing delivery vectors for the efficient delivery and targeting of anticancer drugs for brain, breast and colon cancer. Research in the area of topical nanoparticulate systems in her research group includes developing lipid nanostructures for deeper skin layer targeting for various dermatological diseases including atopic dermatitis and psoriasis. She has utilised drug delivery strategies like microspheres, in-situ gelling agents, liquid crystalline systems and oily injections for developing long acting parenterals. She is also interested in applying advanced drug delivery technologies to traditional herbal drugs to develop Nonophytomedicines.

Conferences

  • Attended over 150 conferences.
  • Presented over 250 research presentations and over 50 invited lectures at scientific meetings and conferences.

External Activities

Kamalinder serves on International Steering Committee for “Handbook of Pharmaceutical Excipients”, joint publication by AAPS, Pharmaceutical Press, and Royal Pharmaceutical Society, Great Britain. She has contributed 5 monographs 5th edition (2005), 10 monographs 6th edition (2009) and 15 monographs for 7th edition (2013) and currently working on 20 monographs for the eighth edition.