Navigation

Explore our research

  • Lancashire Clinical Trials Unit (CTU)

The Lancashire Clinical Trials Unit (CTU) has been set up to manage health related trials for UCLan and external organisations. The Lancashire CTU team has accrued many years of experience in the skills required to develop, manage and analyse clinical trials with a growing specialisation in trials of complex interventions, in particular feasibility trials. The formulation of the Lancashire CTU structure was initiated in 2012 and we are currently supporting national and international trials.

The Lancashire CTU offers a quality assured service for the coordination and delivery of key services pertaining to robust clinical trials of complex interventions and other well designed studies.

 We offer support in:

  • Trial design and developing collaborative applications to funders
  • Trial and site set-up and on-going management, including oversight monitoring
  • Randomisation
  • Data management (including form (CRF) design, data entry and data cleaning)
  • Statistical analysis and reporting

These services are underpinned by our robust quality assurance processes

We specialise in complex intervention trials in the topic areas of:

  • Stroke
  • Midwifery
  • Cancer
  • Musculoskeletal health
  • Public/population health
  • Mental health

We would consider collaborations in other areas of health research.

If you are interested in engaging with the Lancashire Clinical Trials Unit then please apply for our support using the Lancashire CTU request form as early as possible. The completed form should be emailed to lancashirectu@uclan.ac.uk

Lancashire Clinical Trials Unit group photo

Expertise and Subject Areas

  • Trial design and development
  • Feasibility trials
  • Complex intervention trials
  • Trial management
  • Data management
  • Statistics
  • Trial Reporting
  • Research
  • Quality Assurance

Publications

Beaver K, Williamson S, Sutton C, Hollingworth W, Gardner A, Allton B, Abdel-Aty M, Blackwood K, Burns S, Curwen D, Ghani R, Keating P, Murray S, Tomlinson A, Walker B, Willett M, Wood N, Martin-Hirsch P (2016) Comparing hospital and telephone follow-up for patients treated for stage–I endometrial cancer (ENDCAT trial): a randomised, multicentre, non-inferiority trial. British Journal of Obstetrics and Gynaecology DOI: 10.1111/1471-0528.14000. View publication

Muñoz-Venturelli P, Arima H, Lavados P, Brunser A, Peng B, Cui L, Song L, Billot L, Boaden E, Hackett M.L, Heritier S, Jan S, Middleton S, Olavarría V.V, Lim J Y, Lindley R.I, Heeley E, Robinson T, Pontes-Neto O, Natsagdorj L, Lin R-T, Watkins C, Anderson C S, and for the HeadPoST Collaborative Investigators (2015). Head Position in Stroke Trial (HeadPoST) – sitting-up vs lying-flat positioning of patients with acute stroke: study protocol for a cluster randomised controlled trial. Trials, 16, 256. View publication

Radford, Kathryn A, Phillips, Julie, Jones, Trevor, Gibson, Ali, Sutton, Chris J, Watkins, Caroline Leigh, Sach, Tracey, Duley, Lelia, Walker, Marian, Drummond, Avril, Hoffman, Karen, O'Connor, Rory, Forshaw, Denise and Shakespeare, David (2015) Facilitating return to work through early specialist health-based interventions (FRESH): protocol for a feasibility randomised controlled trial. Pilot and Feasibility Studies, 1, 24. View publication

Chesworth, Brigit, Leathley, Michael John, Thomas, Lois Helene, Sutton, Chris J, Forshaw, Denise and Watkins, Caroline Leigh (2015) Assessing fidelity to treatment delivery in the ICONS (Identifying Continence OptioNs after Stroke) cluster randomised feasibility trial. BMC Medical Research Methodology, 15, 68. ISSN 1471-2288 View publication

The AVERT Trial Collaboration group. Efficacy and safety of very early mobilisation within 24 h of stroke onset (AVERT): a randomised controlled trial (2015) The Lancet 2015; 386(9988):46-55 View publication

Lois H Thomas, Caroline L Watkins, Beverley French, Christopher Sutton, Denise Forshaw, Francine Cheater, Brenda Roe, Michael J Leathley, Christopher Burton, Elaine McColl and Jo Booth for The ICONS Project Team and the ICONS Patient, Public and Carer Involvement Groups (2011) Study protocol: ICONS: Identifying continence options after stroke: A randomised trial. Trials 12: 131. View publication

Events and News

22nd November 2016
Lancashire CTU training day

14th September 2016
Good Clinical Practice (GCP) Training

12th July 2016
The Health and wellbeing Research Methodology and Implementation (HeRMI) seminar, 12th July 2016 Title of the seminar is: Trial Site selection: Engaging clinical staff in complex interventions.

15 February 2015

Lancashire CTU training day, Westleigh Conference Centre, University of Central Lancashire

September 2014
Role of emergency care staff in managing acute stroke 

18 June 2014
Stroke nurses to take part in global trial of patient positioning policies. (Nursing Standard)

16 June 2014
University hosts county’s new clinical trials unit

12 June 2014
UCLan launches Lancashire’s first Clinical Trials Unit

12 June 2014
Lancashire Clinical Trials Unit Launch Event 

Members

Directors

Prof. Caroline Watkins (Director)
Dr Chris Sutton (Associate Director Operations / Principal Statistician)

Trial Management

Denise Forshaw (Principal Clinical Trials Manager)
Joanna Cox (Clinical Trials Manager)
Jane Fitzgerald (Senior Trials Assistant)
John Heney (Senior Trials Assistant)

Trial Design and Statistical Analysis

Dr Chris Sutton (Principal Statistician)
Svetlana Tishkovskaya (Statistician)
Jane Burnell (Senior Statistical Assistant)
Laura Howell (Research Associate in Medical Statistics)

Information Systems and Data Management

Dr Mal Auton (Data Manager)
Alison Hadley (Data Co-ordinator)
Glenn Holt (Senior Clinical IS Assistant)

Quality Assurance

George Georgiou (Quality Assurance and Training Manager)

Administration

Simone Finley (Senior Associate Research Officer)
Carole Bruce (Data Entry)
Alison Gibbon (Data Entry)
Helen Byfield (Data Entry)
Rosemary Horan (Data Entry)
Dr Hayley Tyrer (Business and Operations Manager)

Projects

  • FRESH
  • HeadPoST
  • TREAT-UI
  • ADOPTS
  • ICARE
  • A-GLOVES
  • EXERGAMES