School of Medicine
Harrington Building, HA117
+44 (0) 1772 89 6134
Subject Areas: Biosciences
Dr Emyr Bakker joined the School of Medicine in December 2017 after four and a half years of teaching and research experience at the University of Salford. Emyr teaches primarily biochemistry and cell biology across a number of modules and degrees within the School, and is the Deputy Course Lead for the Integrated Masters in Physician Associate Studies (MPAS) degree. His research expertise is in bioinformatics, molecular endocrinology and cancer biology, with a focus on mesothelioma and leukaemia.
Emyr started his research career during his PhD at the University of Salford, where he employed an interdisciplinary approach of computational biology and wet laboratory methodologies to investigate mechanisms of microenvironment-induced chemotherapy resistance in paediatric leukaemia, whilst also dedicating a focus to elucidating causes of glucocorticoid hormone resistance. Part of his research was to build predictive models that aimed to predict a patient’s response to chemotherapy. These findings have since been published.
Following the submission of his PhD thesis, Emyr worked on a project funded by the British Lung Foundation, where he investigated the role of hypoxia-related microRNAs in mesothelioma (a very rare cancer that is heavily tied to asbestos exposure). This research is ongoing and Emyr holds a Visiting Researcher position at the University of Salford to facilitate collaborative research interest. Numerous other projects are ongoing with national and international collaborators, which are expected to be published in 2018-2019.
In addition to the basic science research described previously, Emyr has written several articles describing the state of clinical trials for different cancers, as well as co-authored opinion pieces on where he and his colleagues believe research efforts should be focussed, and has also contributed towards a meta-analysis where he analysed clinical trials via Cochrane bias assessment (to be published). Although Emyr’s primary experience is in preclinical wet and dry research, he is always open to learning new skills and forming collaborations at any level of research, as well as exploring new fields outside of his main expertise in cancer biology.
In terms of teaching, Emyr is an Associate Fellow of the Higher Education Academy and is currently working towards Fellow status. He was awarded Best Postgraduate Teacher at Salford University in 2017 and has several years of experience in supervising and mentoring junior research scientists such as project students. Emyr greatly enjoys teaching and is an advocate for reflective teaching practice. His current teaching is primarily biochemistry and cell biology on the MBBS, MPAS, BSc (Hons) Medical Sciences and Physician Associate postgraduate programmes.
Qattan, Malak Yahia , Bakker, Emyr , Rajendran, Ramkumar , Chen, Daphne Wei-Chen, Saha, Vaskar , Liu, Jizhong, Zeef, Leo, Schwartz, Jean-Marc , Mutti, Luciano et al (2017) Differential regulation of cell death pathways by the microenvironment correlates with chemoresistance and survival in leukaemia. PloS one, 12 (6). e0178606.
Bakker, Emyr , Tian, Kun, Mutti, Luciano, Demonacos, Constantinos , Schwartz, Jean-Marc and Krstic-Demonacos, Marija (2017) Insight into glucocorticoid receptor signalling through interactome model analysis. PLoS computational biology, 13 (11). e1005825. ISSN 1553-734X
Bakker, Emyr , Guazzelli, Alice, Ashtiani, Firozeh, Demonacos, Constantinos , Krstic-Demonacos, Marija and Mutti, Luciano (2017) Immunotherapy advances for mesothelioma treatment. Expert Review of Anticancer Therapy, 17 (9). pp. 799-814. ISSN 1473-7140
Bakker, Emyr , Qattan, Malak , Mutti, Luciano, Demonacos, Constantinos and Krstic-Demonacos, Marija (2015) The role of microenvironment and immunity in drug response in leukemia. BBA - Biochimica et Biophysica Acta, 1863 (3). pp. 414-426. ISSN 0006-3002
I have been an active conference participant since the start of my research career and have attended and presented work at numerous national and international conferences, such as the Society for Endocrinology (British Endocrine Society) and the Nuclear Receptors conference organised by the European Molecular Biology Organisation.