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Phil Roberts

Dr. Phil Roberts

Principal Lecturer; Academic Lead Archaeology, Biology and Geography

School of Forensic and Applied Sciences

Maudland Building, MB061

+44 (0) 1772 89 5804

proberts1@uclan.ac.uk

Phil is a pharmacologist by training and is a principal lecturer if the School of Forensic and Applied Sciences. He has teaching experience in the areas of physiology, pharmacology, toxicology, biochemistry and general biology at all levels form year one undergraduate to postgraduate programmes. His research interests include the role of drug metabolism in the generation of toxic metabolites, toxicokinetics and DNA polymorphism, neurotoxicology and the chemosensitivity of neuronal tumours.

Phil completed his undergraduate training at Liverpool University where he graduated with a first class honours degree in Pharmacology in 1987. He then completed a PhD on the role of metabolism in the toxicity of mianserin in the same department which was awarded in 1981. This was followed by postdoctoral posts at Fisons plc (1990-91) and the University of Glasgow (investigating the effects of cryopreservation on hepatocyte functionality; 1991-93) before securing a lectureship post in the Department of Biological Sciences at the University of Central Lancashire. Whilst in this department he Ire-designed the BSc (Hons) Biomedical Science degree so that it could qualify for National Accreditation status by the two professional bodies involved (IBMS and CPSM). This was achieved successfully through substantial changes to the existing programme with the development of modules to enhance the teaching of Biomedical Science and to meet the professional standards of the subject. This course still provides the University with a strong teaching base in the biomedical field. . During this period he was also responsible for the validation of a Franchise arrangement for the course between this University and the D.Y. Patil Institution in Mumbai.

 In 2003 he moved to the new Dept Forensic and Investigative Science where in his role as programme co-ordinator for Masters courses chaired the Course Development Committee for the validation of three novel Masters courses (MSc DNA Profiling, MSc Document Analysis, MSc Human Remains Identification). These were the first Masters level courses to be offered by this Department and were distinctive in that they are the only ones of their kind to be offered in the UK.

In 2006 he was asked to lead in the development of a School of  Pharmacy in the Faculty of Science which requires accreditation by the Royal Pharmaceutical Society of Great Britain (RPSGB). The accreditation process was successful and the Pharmacy course is now well established within the University.

In 2016 he returned to Forensic and applied sciences and was instrumental in the development of a new Biology provision in the School. He is currently academic lead for Biology and also Geography and Environmental Science and Archaeology

Phil has always strived to conduct research and associated activities  and has published papers in refereed journals and presented at various conferences and have a number of successful completions at postgraduate level. 

He developed a study on chemosensitivity assays to assess toxicological parameters in gliomal cells in collaboration with neuroconsultants at Royal Preston Hospital. This work has involved collaboration with Royal Preston Hospital that has resulted in a Director of Studies role for two of the Neurosurgical Registrars  studying for an MD in the area of chemosensitivity of primary gliomal cell cultures. The work which was started at Preston has attracted both National and International interest and has resulted in the Brain Tumour Northwest which is a collaborative venture between Universities of Central Lancashire and Wolverhampton and Lancashire Teaching Hospitals NHS Trust in a new strategic alliance designed to consolidate and exploit clinical and research-based brain tumour expertise in the region.

Publications

Hood M, Adams D and Roberts P (2015) Design, synthesis and screening of inhibitor of Cytochrome P450 1B1 (CYP1B1) Journal of Chemical and Pharmaceutical Research, 7(2):169-178

Ramaswamy R, Ashton K, Lea R, Roberts P, Davis CH, Golash A, Dawson T. (2012)  Study of effectiveness of mifepristone for glioma cell line growth suppression. Br J Neurosurg. 26(3):336-9

Dawson TP, Iyer RV, Lea RW, Roberts P, Harris E, Ashton K, Golash A, Davis CH. (2010) The MTS vs. the ATP assay for in vitro chemosensitivity testing of primary glioma tumour culture. Neuropathol Appl Neurobiol. 36(6):564-7

Roberts, P., Riley, R.J.,  Swan, R.,  Slee, D. and  Whittaker, S.M. (2006) An Inter-Laboratory Analysis of Nortriptyline CYP Interactions In Vitro Confirms Merits of fuinc Considerations Drug Metabolism Reviews, volume 38, supplement 1, 148-149. Abstracts from the 9th European ISSX Meeting, June 4th-7th 2006, Manchester UK.

More publications

Research Activities

  • Drug Metabolism: The role of drug metabolism in the generation of toxic metabolites. Toxicokinetics and DNA polymorphism
  • Toxicology: Neurotoxicology and chemosensitivity of neuronal tumours.

Teaching activities

  • Pharmacology
  • Toxicology
  • Physiology
  • Biochemistry