School of Pharmacy and Biomedical Sciences
Maudland Building, MB241
+44 (0) 1772 89 5829
Dr Shaw is the Senior Lecturer in Pharmacology with research interests including the use of aptamers and micro RNAs for the early diagnosis and treatment of brain tumours. She is part of the Brain Tumour North West research cluster which involves a strategic alliance between UCLan and the Royal Preston Hospital, the Walton Centre and University of Wolverhampton.
The BTNW research cluster is a strategic alliance between partner institutions that bring together academic researchers and clinicians into one critical mass to share expertise, knowledge and undertake collaborative projects into brain tumour research. The Neuro-oncology research group at UCLan is performing cutting edge research investigating several novel therapeutics, delivery systems and diagnosis regimens for brain tumours. Dr Shaw is currently involved in the use of aptamers as diagnostic and therapeutic agents for all grades of adult and paediatric brain tumours and also the use of micro RNA’s as biomarkers for brain tumour diagnosis and prognosis.
1. Aptekar S, Arora M, Lawrence CL, Lea RW, Ashton K , Dawson T, Alder JE, Shaw L (2015). Selective Targeting to Glioma with Nucleic Acid Aptamers. PLoS One. Aug 7;10(8):e0134957. doi: 10.1371/journal.pone.0134957. eCollection 2015.
2. Hayes J, Thygesen H, Tumilson C, Droop A, Boissinot M, Hughes TA, Westhead D, Alder JE, Shaw L>, Short SC, Lawler SE (2015). Prediction of clinical outcome in glioblastoma using a biologically relevant nine-microRNA signature. Mol Oncol. 2015 Mar;9(3):704-14. doi: 10.1016/j.molonc.2014.11.004. Epub 2014 Nov 28
3. Tumilson CA, Lea RW, Alder JE, Shaw L. (2014). Circulating microRNA biomarkers for glioma and predicting response to therapy.. 2014 Oct;50(2):545-58. doi: 10.1007/s12035-014-8679-8. Epub 2014 Apr 3
Lisa has produced a One Minute Research video about her research into circulating microRNAs and aptamers for the diagnosis and potential treatment of brain tumours