School of Forensic and Applied Sciences
Kirkham Building, KM105
+44 (0) 1772 89 4024
Subject Areas: Allied Health, Biosciences, Pharmacy and Pharmacology
Claire is a Pharmacologist with a specific interest in understanding the mechanisms of drug toxicity in humans and the environment. Her research involves the use of in vitro and computational toxicology methods in order to develop screening tools to aide in drug development and hazard assessment strategies.
Claire completed her PhD in Pharmacology and Therapeutics as part of the Medical Research Centre at the University of Liverpool, where she studied toxicology of drugs. During her postdoctoral years she work as a computational toxicologist on many European wide projects as part of a multidisciplinary team. Her research has focused on both the human and environmental impacts of drugs and chemicals, evidenced by high impact publications in this field. Currently a Lecturer at UCLAN she aspires to instil passion for understanding toxicology into her students.
Teaching activities and responsibilities
SEURAT-1 and COSMOS consortium meetings (Barcelona, 2014, 2015; Liverpool, 2015); International Environmental Omics conference (Liverpool, 2014); EDRISK meeting (Oslo, 2014); EUROTOX conference (Edinburgh, 2014); British Toxicology Society conference (Warwick, 2012).
Mellor, Claire , Marchese Robinson, Richard, R, Benigni, Ebbrell, D, Enoch, S.J., Firman, J.W., Madden, J.M., Pawar, G, Yang, C et al (2019) Molecular Fingerprint-Derived Similarity Measures for Toxicological Read-Across: Recommendations for Optimal Use. Regulatory Toxicology and Pharmacology, 101 . pp. 121-134. ISSN 0273-2300
Pletz, J, Enoch, S.J, Jais, D.M, Mellor, Claire , Pawar, G, Madden, J.C, Webb, S.D, Tagliati, C and Cronin, M.T.D (2018) A critical review of adverse effects to the kidney: mechanisms, data sources and in silico tools to assist prediction. Expert Opinion on Drug Metabolism & Toxicology . ISSN 1742-5255
Nelms, Mark, Mellor, Claire , Enoch, Steven, Judson, Richard, Patlewiczd, Grace, Madden, Judith, Cronin, Mark and Edwards, Stephen (2018) A Mechanistic Framework for Integrating Chemical Structure and High-Throughput Screening Results to Improve Toxicity Predictions. Computational Toxicology .
Cronin, M.T.D, Enoch, S.J, Mellor, Claire , Przybylak, K, Richarz, A-N and Madden, J.C (2017) In Silico Prediction of Organ Level Toxicity: Linking Chemistry to Adverse Effects. Toxicology Research, 33 (3). pp. 173-182. ISSN 2045-4538