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Dr. Claire Mellor

Lecturer In Cell Biology

School of Psychology

Darwin Building, DB215

+44 (0) 1772 89 4024

Cmellor3@uclan.ac.uk

Subject Areas: Allied Health, Biosciences, Pharmacy and Pharmacology

Claire is a Pharmacologist with a specific interest in understanding the mechanisms of drug toxicity in humans and the environment. Her research involves the use of in vitro and computational toxicology methods in order to develop screening tools to aide in drug development and hazard assessment strategies.

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Claire completed her PhD in Pharmacology and Therapeutics as part of the Medical Research Centre at the University of Liverpool, where she studied toxicology of drugs. During her postdoctoral years she work as a computational toxicologist on many European wide projects as part of a multidisciplinary team. Her research has focused on both the human and environmental impacts of drugs and chemicals, evidenced by high impact publications in this field. Currently a Lecturer at UCLAN she aspires to instil passion for understanding toxicology into her students.

  • Ph.D. Pharmacology and Therapeutics, University of Liverpool, 2014
  • M.Res. Masters of Research, Drug Safety Science, University of Liverpool, 2010
  • B.Sc. Pharmacology and Therapeutics, University of Liverpool, 2009

Teaching activities and responsibilities 

Module contributions

  • FZ1601 – Introduction to Cell Biology
  • FZ1604 – Science and Society
  • FZ1014 – Biology for Forensic Scientists
  • FZ2604- Human Physiology and Disease
  • FZ2606- Introduction to Pharmacology and Cell Culture
  • NT2031- Research Theory and Practice
  • NT3008/FZ3699- Biology Dissertation
  • NT3501- Forensic Science Dissertation
  • NT3011- Fieldwork (Stage 2)
  • FZ3602- Ecotoxicology

Conferences

SEURAT-1 and COSMOS consortium meetings (Barcelona, 2014, 2015; Liverpool, 2015); International Environmental Omics conference (Liverpool, 2014); EDRISK meeting (Oslo, 2014); EUROTOX conference (Edinburgh, 2014); British Toxicology Society conference (Warwick, 2012).

Publications

Mellor, Claire  , Marchese Robinson, Richard, R, Benigni, Ebbrell, D, Enoch, S.J., Firman, J.W., Madden, J.M., Pawar, G, Yang, C et al (2019) Molecular Fingerprint-Derived Similarity Measures for Toxicological Read-Across: Recommendations for Optimal Use. Regulatory Toxicology and Pharmacology, 101 . pp. 121-134. ISSN 0273-2300

Pletz, J, Enoch, S.J, Jais, D.M, Mellor, Claire  , Pawar, G, Madden, J.C, Webb, S.D, Tagliati, C and Cronin, M.T.D (2018) A critical review of adverse effects to the kidney: mechanisms, data sources and in silico tools to assist prediction. Expert Opinion on Drug Metabolism & Toxicology . ISSN 1742-5255

Nelms, Mark, Mellor, Claire  , Enoch, Steven, Judson, Richard, Patlewiczd, Grace, Madden, Judith, Cronin, Mark and Edwards, Stephen (2018) A Mechanistic Framework for Integrating Chemical Structure and High-Throughput Screening Results to Improve Toxicity Predictions. Computational Toxicology .

Cronin, M.T.D, Enoch, S.J, Mellor, Claire  , Przybylak, K, Richarz, A-N and Madden, J.C (2017) In Silico Prediction of Organ Level Toxicity: Linking Chemistry to Adverse Effects. Toxicology Research, 33 (3). pp. 173-182. ISSN 2045-4538

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