The International Anxiety and Depression Epidemiological Study in Cystic Fibrosis (TIDES - CF)

This study aims to:

  • Estimate the prevalence of depression and anxiety in patients with CF ages 12 through to adulthood and parent caregivers of children with CF ages birth to 18.
  • Identify risk factors associated with symptoms of depression and anxiety.
  • Evaluate how depression and anxiety influence health outcomes (particularly number of exacerbations and hospitalizations, lung function and nutritional measures).

Project lead

Professor Janice Abbott

Project Staff

Dr Margaret Hurley


Royal Liverpool and Broadgreen University Hospitals NHS Trust; UK Cystic Fibrosis Trust


Janice Abbott is Co-lead for the UK arm of this international study with Dr Alistair Duff, Leeds NHS Trust and Carolyn Cowperthwaite, Broadgreen Hospital NHS Trust.

National collaborators: Clare Sumner, 39 Cystic Fibrosis Centres in the UK

International collaborators: Professor Alexandra Quittner, University of Miami, US; Professor Lutz Goldbeck, University of Ulm, Germany; Dr Patrick Lambrecht, Belgium; Dr Paola Catastini, Italy; Drs Mónica Cebrián & Amparo Sole, Spain; Dr Agneta Bergsten Brucefors, Sweden: Drs Marijke Tibosch, Mees van Schravendijk, The Netherlands; Dr Hasan Yüksel, Turkey.