By carefully selecting a set of lipid molecules one can engineer and thereby predict their behavior for self-assembling nanostructures. The classical phase behavior of various lipids can be further fine tuned by adding chemical and biological molecules and by modulating physicochemical triggers such as, temperature, pressure and shear.
Our projects involve basic understanding, calculation of molecular level parameters, fine tuning and application driven studies of lipid nanostructural behavior.
Kulkarni,C.V*, Y. Patil-Sen, M.V. Kulkarni and A. Iglic. (2015) Biophys. J, 108 (2) Supplement 1 p544a.
Engineering Bicontinuous Cubic Structures at the Nanoscale– the Role of Chain Splay
Kulkarni, C.V., T. Y. Tang, A. M. Seddon, J.M. Seddon, O. Ces, and R. H. Templer.* (2010) Soft Matter, 6: 3191-3194
Nanostructural Studies on Monoelaidin-Water Systems at Low Temperatures
Kulkarni, C.V.* (2011) Langmuir, 27(19):11790-800
Monoolein: A Magic Lipid?
Kulkarni, C.V.*, W. Wachter, G. R. Iglesias, S. Engelskirchen and S. Ahualli. (2011) Phys. Chem. Chem. Phys., 13 (8): 3004-3021
Lipid Crystallization: From Self Assembly to Hierarchical and Biological Ordering
Kulkarni, C.V.* (2012) Nanoscale, 4, (19): 5779-5791.