• Surface Patterning

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Fabrication of nanostructures and their surface patterning with chemicals and bio-chemicals in the nanometer length has a fundamental importance in nanotech and nanobiotechnology.

The fabrication of nanoporous / nanoparticulate composites and their applications via surface patterning with chemicals and bio-chemicals has a direct impact for the applications in chemistry and biosciences. Surface patterning on particles in suspension can be a complex process due to the aggregation of the particles and their Brownian motion in the suspension. This group is interested on the formation of patterned surfaces and their modification with chemical / biochemical functionalities for highly specific and targeted applications such as bio-sensor, food technology, nanomedicine, magnetic bio-separation, green/ environmental chemistry and industrial catalysis.


Recent Conference presentations:

  • Dr Tapas Sen: Nanocomposites based Clean Water Technology: International Conference in Nanoscience and Nanotechnology; (NSTI 2013) Washington DC USA May 2013.
  • Dr Tapas Sen: Nanotechnology in Health, Environment, Industrial and Forensic Science, Indian Association for the Cultivation of Science, December 2012.
  • Dr Tapas Sen: Nanotechnology in Health, Environment, Industrial and Forensic Sciences: National Chemical Laboratory Innovation Hun, India December 2012.
  • Dr Tapas Sen: Nanotechnology in Health, Environmental, Industrial and Forensic Sciences: Shiv Nada University India December 2012.
  • Dr Tapas Sen: Water treatment- Nanocomposites for the treatment of industrial and municipal sewage water; Shenzhen Virtual University Park China November 2012.
  • Dr Tapas Sen: Novel Hierarchically Ordered Vandao-Silicate Nanocomposites for the Application in Industrial Catalysis (NSTI-Nanotech 2012) San Jose California USA June 2012.
  • Dr Tapas Sen: Nanoparticles in Clean Water Tech; Fudan University, China May 2012 (Distinguished Lecture).

Publications and Outputs

This is a selection of recent publications. Further information about group members publications can be accessed via the staff profiles in the members section, which link to the institutional repository.


  • T Sen, IJ Bruce “Surface Engineering of Nanoparticles in Suspension for particle based biosensing” Scientific Reports 2:564
  • T Sen, SJ Sheppard, T Mercer, M Eizardi-sharifabad, M Mahmoudi, A Elhissi “Simple one-pot fabrication of ultra-stable core-shell superparamagnetic nanoparticles for potential application in drug delivery” RSC Advances 2.5221
  • J Mondal, T Sen, A Bhaumik “Fe304@mesoporous SBA-15: A robust and magnetically recoverable catalyst for One-Pot synthesis of 3,4-Dihydropyrimidin-2(1H)-ones via Biginelli reaction” Dalton Trans, 41.6173
  • M Howard, J Whittle, F Zhang, DYZhao, T Sen: “Novel Hierarchically Ordered Porous Vanadao-silicate nanocomposites for the application in Industrial Catalysis ISBN 978-1-4665-6274-5 vol2 2012 pg 495-498, CRC press, Taylor and Francis group (Book Chapter authored)
  • M Howard, J Whittle, F Zhang, DY Zhao, T Sen: “Microwave assisted oxidation catalysis of bulky organic molecules using hierarchically ordered porous Vanado-Silicate Nanocomposites” Journal of Nanoparticle Research (selected from NSTI 2012 for an invited submission)
  • M Howard, J Whittle, F Zhang, DUZhao, T Sen “Novel Hierarchically Ordered Porous Vanado-Silicate Nanocomposites for the Application in Industrial Catalysis. Proceedings on NSTI-Nanotechn 2012, San Jose, California, USA , June 2012 (peer-reviewed conference proceedings)


  • M. Mahmoudi, S. Sant, B. Wang, S. Laurent, T. Sen “Superparamagnetic iron oxide nanoparticles (SPIONs): Development, surface modification and applications in chemotherapy” Advanced Drug Delivery Reviews 63, 24, (2011).
  • F. Casula, A. Corrias, P. Arosio, A. Lascialfari, T. Sen, P. Floris, I. J. Bruce “Design of Water-based Ferrofluids as contrast Agents for Magnetic Resonance Imaging Maria” Journal of Colloid and Interface Science 357, 50 (2011).
  • D. Rother, T. Sen, D. East, I. J. Bruce “Silicon, silica and its surface patterning with alkoxysilanes for nanomedical applications” Nanomedicine 6, 281 (2011).


  • Sen T., Bruce I.J., Mercer T. “Fabrication of novel hierarchically ordered porous magnetic nanocomposites for bio-catalysis” Chem. Commun. 46 (2010) 6807.
  • Mahmoudi M., Sant S., Wang B., Laurent S. , Sen T., “Superparamagnetic iron oxide nanoparticles (SPIONs): Development, surface modification and applications in chemotherapy” Adv. Drug. Deliv. Rev., (2010) doi:10.1016/j. addr.2010.05.006
  • Sen T. “Novel Nanocomposites: Hierarchically Ordered Porous Silica for the Immobilisation of Enzyme as Bio-catalyst” NSTI-Nanotech 2010, www.nsti.org., ISBN 978-1-4398-3401-5 ,1 (2010) 784, CRC press, Taylor & Francis group.
  • Sen T., Sheppard S., Mercer T., Elhissi A., “Magnetoliposomes: Stability of magnetic nanoparticles in suspension for drug delivery”NSTI-Nanotech 2010, www.nsti.org., ISBN 978-1-4398-3401-5, 1 (2010) 924, CRC press, Taylor & Francis group.
  • Sen T. and Bruce I. J., “A generalized approach for the surface engineering of nanoparticles in suspension for highly efficient hybrid capture of bio-molecules” NSTI-Nanotech 2010, www.nsti.org., ISBN 978-1-4398-3401-5,.1 (2010) 596, CRC press, Taylor & Francis group.


Staff from across the University form the Institute, bringing together a wealth of experience. Staff with a particular interest in surface patterning are:

Associate Members

StJohn Crean

Jenny Redman

Monica Avila

Lingzhi Wang

PhD Students

Ben Hodgson

Maneea Eizadi

Qurban Ali

Amritvir Kaur

Gareth Morris-MChem student

Eric Jones- MChem student

Related Projects

Multifunctional Nanocomposites for the Separation of Pollutants from Industrial Municipal Sewage Water – joint project with Fudan University, Shanghai China.

Immobilisation of biomolecules on magnetisable solid supports for applications in bio-catalysis and bio-sensors – joint project with Q-bioanalytic Germany.

Host-guest chemistry inside the hierarchically ordered porous vanado-silicate.

Transition metal containing hierarchically ordered porous materials for oxidation catalysis
Field and frequency dependent bio-catalysis and drug delivery.

Core-shell biocompatible superparamagnetic iron oxide nanoparticles (SPIONs) for drug delivery.