Translational Biomedical Sciences
Biomedical sciences encompasses various disciplines including pathology, medical microbiology, clinical biochemistry and haematology & transfusion sciences.
To address such disciplines, different applied and translational sciences have emerged.
For instance, biospectroscopy in diagnostic/screening settings or nanomedicine towards novel therapies, which are applied in the important areas of neurodegeneration, medical microbiology and oncology.
Here at UCLan, we have several active research teams working at the cutting edge of these disciplines. Our main focus is to translate laboratory research to applications of benefit in the clinic and in healthcare.
Kamalinder’s research focuses to address the problems of the tropical disease Malaria where she has developed functionalised nanoparticulate drug delivery systems
Members of the School of Pharmacy and Biomedical Sciences were nominated as finalists in the North West Coast Research and Innovation awards in the ‘Partnership in Innovation’ award category which recognises a partnership between an NHS and a non-public sector organisation.
A new joint research trial by Alder Hey and the University of Central Lancashire (UCLan) is using 3D printed placebo tablets to test ‘swallowability’ and acceptance in children between four and twelve years of age, and this may have the potential to enable healthcare professionals to specifically tailor medication for young people, improving patient outcomes and reducing wastage.
Two new members join Professor Kamalinder Singh’s research on a prestigious Split site PhD Commonwealth Scholarship, funded by the Department for International development. The amount awarded for the two fellowships for the year-long project is £73,165 (which equates to £ 26,400 student allowance plus £46,765 tuition and bench fees). Karan Razdan will do research into functionalized Nanoantibiotics for chronic wound infections, Komal Saini will investigate nanocarrier mediated formulations of white curcumin for atopic dermatitis.
Dr Tamara Zwain presented her work on ‘’Development of selective novel DNA functionalised nanostructure lipid carrier formulation for targeted glioblastoma therapy with enhanced permeability through a 3D in-vitro BBB model and penetration of 3D spheroids’’ at the Early Career Researcher’s Meeting at Glasgow hosted by The University of Strathclyde and the British Society for Nanomedicine in July 2019.
The work was part of doctoral research carried out under the supervision of Professor Kamalinder K Singh and Dr Jane Alder. Tamara is currently working to develop functionalised nanoparticles as a novel drug delivery to treat brain cancer and a selective treatment for glioblastoma. Also, she has worked in developing and screening nanoparticles and aptamers through 2D cell lines, 3D spheroids and 3D in-vitro BBB models. Her research interest is developing in-vitro 3D models and nanoparticles for novel drug delivery.
Dr Amina Ferraz is working with Alder Hey Children’s Hospital to develop a better understanding of how children inhale and this represents a move towards personalised inhaled therapy for paediatric patients with asthma. This new joint research study is investigating the impact of age, breathing pattern, disease severity and competency in use, as well as type of spacer device, on drug deposition in the lungs of children aged between 5 and 16 and suffering from asthma.