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The International Anxiety and Depression Epidemiological Study in Cystic Fibrosis (TIDES - CF)

This study aims to:

  • Estimate the prevalence of depression and anxiety in patients with CF ages 12 through to adulthood and parent caregivers of children with CF ages birth to 18.
  • Identify risk factors associated with symptoms of depression and anxiety.
  • Evaluate how depression and anxiety influence health outcomes (particularly number of exacerbations and hospitalizations, lung function and nutritional measures).


Project lead: Professor Janice Abbott

Project staff: Dr Margaret Hurley

Royal Liverpool and Broadgreen University Hospitals NHS Trust; UK Cystic Fibrosis Trust

Janice Abbott is Co-lead for the UK arm of this international study with Dr Alistair Duff, Leeds NHS Trust and Carolyn Cowperthwaite, Broadgreen Hospital NHS Trust.

National collaborators: Clare Sumner, 39 Cystic Fibrosis Centres in the UK

International collaborators: Professor Alexandra Quittner, University of Miami, US; Professor Lutz Goldbeck, University of Ulm, Germany; Dr Patrick Lambrecht, Belgium; Dr Paola Catastini, Italy; Drs Mónica Cebrián & Amparo Sole, Spain; Dr Agneta Bergsten Brucefors, Sweden: Drs Marijke Tibosch, Mees van Schravendijk, The Netherlands; Dr Hasan Yüksel, Turkey.