Molecular Biophysics

The groups focus is on understanding structure function relationships of amphiphilic bioactive molecules and the design of new biomaterials. The group is multidisciplinary and draws on a range of specialisms including, biology, (cell biology and microbiology), chemistry (biochemistry, synthetic chemistry), physics (biophysics, nano physics) and computational modelling to:

  • Investigate the mode of action of helical peptides and other bioactive amphiphilic molecules and to identify their molecular target(s)
  • Undertake structure-activity studies to improve the antimicrobial activity and oncolytic properties of amphiphilic, membrane interactive compounds
  • Develop computational methods for the identification and assessment of key functional characteristics of amphiphilic molecules with medical applications