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Lipid Phase Behaviour

lipid-nanostructure-lipid-phase-behaviour

Lipid Phase Behaviour

By carefully selecting a set of lipid molecules, one can engineer and thereby predict their behaviour for self-assembling nanostructures. The classical phase behaviour of various lipids can be further fine-tuned by adding chemical and biological molecules and by modulating physicochemical triggers such as, temperature, pressure and shear.

Our projects involve basic understanding, calculation of molecular level parameters, fine-tuning and application driven studies of lipid nanostructural behaviour.

Related Publications

Biomolecules Altering the Lipid Molecular Shape in Model Non-Lamellar Membranes Kulkarni,C.V*, Y. Patil-Sen, M.V. Kulkarni and A. Iglic. (2015) Biophys. J, 108 (2) Supplement 1 p544a.

Engineering Bicontinuous Cubic Structures at the Nanoscale– the Role of Chain Splay Kulkarni, C.V., T. Y. Tang, A. M. Seddon, J.M. Seddon, O. Ces, and R. H. Templer.* (2010) Soft Matter, 6: 3191-3194

Nanostructural Studies on Monoelaidin-Water Systems at Low Temperatures Kulkarni, C.V.* (2011) Langmuir, 27(19):11790-800

Monoolein: A Magic Lipid? Kulkarni, C.V.*, W. Wachter, G. R. Iglesias, S. Engelskirchen and S. Ahualli. (2011) Phys. Chem. Chem. Phys., 13 (8): 3004-3021

Lipid Crystallization: From Self Assembly to Hierarchical and Biological Ordering Kulkarni, C.V.* (2012) Nanoscale, 4, (19): 5779-5791.