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Dr. Yogita Patil-Sen

Daphne Jackson Fellow

School of Physical Sciences and Computing

Maudland Building, MB210

+44 (0) 1772 89 3736

ypatil-sen@uclan.ac.uk

Subject Areas: Chemistry

Yogita is an experimental chemist whose research focuses on design and development of self-assembled nanostructures for healthcare applications. She is research active within the area of Biological Materials Research Group.

Yogita has also covered teaching duties, these modules included

  • FZ1024 (UG, Forensic Chemistry module)
  • FZ4004 (PG, Forensic Toxicology and Instrumental Analysis)
  • FZ4603 (PG, Molecular Spectroscopy)

Full Profile

Yogita obtained her BSc (Hons) in Chemistry and MSc in Inorganic Chemistry from the University of Pune, India. She then completed her PhD in Biophysical Chemistry from the University of Manchester. Yogita has undertaken various research and teaching assignments at various top-class academic and research institutes in the world; these include, University of Manchester and University of Central Lancashire, UK, Concordia University, Canada, Weizmann Institute of Science, Israel, and National Chemical Laboratory and University of Pune, India. She has worked on research projects involving self-assembled lipid nanostructures, design and synthesis of antimicrobial and anticancer peptides, pharmaceutical and agricultural formulations, synthesis of biologically important inorganic complexes and theoretical modelling of zeolites. Yogita joined UCLan in 2013 and her current research focuses on developing novel drug delivery systems for cancer therapy. She also teaches chemistry modules at undergraduate and postgraduate level. Yogita has been successfully co-supervising several research students at UCLan.

Memberships

Member of the Royal Society of Chemistry, the American Chemical Society and the Cambridge Association for Women in Science and Engineering.

Research Activities

Yogita’s research interests are in the areas of nanotechnology and bio-medicinal chemistry- synthesis of lipid based and magnetic nanoparticles and their various applications, mainly for cancer therapy.

Projects

Daphne Jackson Fellowship jointly funded by the Royal Society of Chemistry and UCLan,

Project titled “Thermally responsive lipid capped core-shell magnetic nanoparticles for field and frequency triggered drug delivery”.

Conferences 

World Innovation Conference & Expo, Washington, DC, June 14-17, 2015, ‘Nanoparticle based drug delivery'

APS PharmSci 2014, Hatfield, UK, 08-10th September 2014, ‘Development of a novel, multifunctional membrane-interactive pyridinium salt with potent anticancer activity’.

Bicontinuous Cubic Phases Conference, Noosa, Australia, 30th July-2nd August 2014, ‘Nanostructural Characterization of Butter Oil’.

Publications

Yogita Patil-Sen, Amin Sadeghpour, Michael Rappolt, Chandrashekhar V. Kulkarni (2016) “Facile Preparation of Internally Self-assembled Lipid Particles Stabilized by Carbon Nanotubes”, Journal of Visualized Experiments, 108, e53489, doi:10.3791/53489.

Fahs, S., Patil-Sen, Y., Snape T. (2015) “Foldamers as anticancer therapeutics: targeting protein-protein interactions and the cell membrane” ChemBioChem, 16, 1840-1853.

Kulkarni, M., Patil-Sen, Y., Junkar, I., Kulkarni, C.V., Lorenzetti, M. and Iglič, A. (2015) “Wettability Studies of Topologically Distinct Titanium Surfaces”, Colloids and Surfaces B: Biointerfaces, 129, 47-53.

Gaunt, N. P., Patil-Sen, Y., Baker, M. J. and Kulkarni, C. V. (2015) “Carbon nanotubes for stabilization of nanostructured lipid particles”, Nanoscale, 7 1090-1095.

Chandrashekhar V. Kulkarni, Zeinab Moinuddin, Yogita Patil-Sen, Rowan Littlefield and Mitesh Hood (2015) “Lipid-hydrogel films for sustained drug release”, International Journal of Pharmaceutics, 479, 416-421.

Kulkarni, C.V, Patil-Sen, Y., Kulkarni M.V., Iglic. A. (2015) “Biomolecules Altering the Lipid Molecular Shape in Model Non-Lamellar Membranes”, Biophysical Journal, 108 (2) Supplement 1 p544a.

Fahs, S., Rowther, F.B., Dennison, S.R., Patil-Sen, Y., Warr, T. and Snape, T.J. (2014) “Development of a novel, multifunctional, membrane-interactive pyridinium salt with potent anticancer activity”, Bioorganic and Medicinal Chemistry Letters, 24, 3430-3433.

Patil-Sen, Y., Tiddy, G.J.T, Brezesinski, G., and DeWolf, C. (2004) “A monolayer phase behaviour study of phosphatidylinositol, phosphatidylinositol 4-monophosphate and their binary mixtures with distearoylphosphatidylethanolamine”, Physical Chemistry Chemical Physics, 6(7), 1562-1565.

Warshawsky, A., Rogachev, I., Patil, Y., Baszkin, A., Weiner, L., and Gressel, J. (2001) “Copper-specific chelators as synergists to herbicides: 1. Amphiphilic dithiocarbamates, synthesis, transport through lipid bilayers, and inhibition of Cu/Zn superoxide dismutase activity” Langmuir, 17(18), 5621-5635.