School of Pharmacy and Biomedical Sciences
Maudland Building, MB025
+44 (0) 1772 89 3590
Subject Areas: Pharmacy, Food and Nutrition
Mohamed's research focuses the incorporation of the latest advances in material science and electronics in the pharmaceutical field. This is an effort to bridge the gap between drug delivery and pharmaceutical technology on one hand and new materials or new design and production methods such as 3D printing on the other hand. The goal is to break current boundaries of oral drug delivery systems and formulation design and link pharmacy with increasingly smart and digitally connected environment.
Dr Mohamed Albed Alhnan is a lecturer in Pharmaceutics in the School of Pharmacy and Biomedical Sciences. Mohamed worked on his PhD project in University College London (UCL) School of Pharmacy. Mohamed expanded his expertise to the design and optimization of coating systems using natural and commercially available polymers or novel materials. He also worked on protein formulation design and characterization for oral drug delivery and the challenges of maintaining of protein integrity and structural activity during manufacturing, storage as well as in the hostile acidic environment of the stomach.
Dr Mohamed's research activities focus the incorporation of the latest advances in material science and electronics in the pharmaceutical field. In this research, he is trying to bridge the gap between drug delivery and pharmaceutical technology on one hand and new materials such as graphene or new design and production methods such as 3D printing on the other hand. The goal of this effort is to break current boundaries of oral drug delivery systems and formulation design and link pharmacy with increasingly smart and digitally connected environment. This effort can enable the digitalisation of dosage form design and prototyping, innovation of new drug delivery systems that are responsive to biosensors and environmental changes as well as improving the personalization of dosage forms. He has currently filed a patent for novel production methods using 3D printing method. He is currently working on research projects for incorporating graphene into pharmaceutical coating to utilize its superior barrier function, electronic and thermal conductivities. The aim is to innovate ‘smart coating’ with unique pH-, light-, voltage or temperature- responsive abilities.
Above: A demonstration for fabricating theophylline tablet (commonly used in the management of asthma) using Fused Deposition Modelling 3D printer.
Above: Production of world’s first example for enteric table produced by 3D printer (for further information: Okwuosa et al., 2016, Fabricating a Shell-Core Delayed Release Tablet Using Dual FDM 3D Printing for Patient-Centred Therapy, Pharm Res, (doi:10.1007/s11095-016-2073-3))
His research activities also cover the development of novel dosage forms based on nano-structures. This includes the development of nano-coating system, the fabrication of solid lipid nanoparticles for anti-arthritis delivery and cancer targeting, and the scale-up production of nanosomes. It also covered developing specific coating system for oral delivery of vaccines, probiotics as well nutraceutical products. I am currently filing another patent to provide a novel solution for nutraceutical and food supplement industries.
He is also a registered pharmacist and a member of the Royal Pharmaceutical Society of Great Britain.
PhD. Pharmaceutics, UCL School of Pharmacy, 2011
Post-graduate diploma in Pharmacy, University of Brighton, 2010
BPharm, University of Aleppo, 2001
Katarzyna Czarnocka, Mohamed A Alhnan, 2015. Gastro-Resistant Characteristics of GRAS-Grade Enteric Coatings for Pharmaceutical and Nutraceutical products. International journal of pharmaceutics (in Press).
Rikhav Gala, Iftikhar Khan, Abdelbary Elhissi, Mohamed A. Alhnan, 2015. A Comprehensive Production Method of Self-cryoprotected Nano-Liposome Powders. International journal of pharmaceutics (in press).
Justyna Skowyra, Katarzyna Pietrzak., Mohamed A. Alhnan, 2015. Fabrication of extended-release patient-tailored prednisolone tablets via fused deposition modelling (FDM) 3D printing. European journal of pharmaceutical sciences.
Mohamed A. Alhnan, Erfan Kidia, Abdul W. Basit Spray-drying enteric polymers from aqueous solutions: A novel, economic and environmentally friendly approach to produce pH-responsive microparticles, Eur J Pharm Biopharm. 2011 Oct;79(2):432-9.
Dr Mohamed's research activities focus on facing the environmental challenges of pharmaceutical dosage form development and manufacturing. In this research, the bridge the gap between green chemistry/manufacturing and dosage form development. The goal of this effort is to develop new manufacturing methods that are more environmentally friendly starting from purpose conscious dosage form design as well as making the use of naturally available materials as substitutes for current artificial medically graded pharmaceutical excipients.
This research also involves the development of novel dosage forms based on nano-structures. It is the marriage of micro- and nano-encapsulation technology with standard industrial pharmaceutical technology. This marriage is essential to bring the latest developments in nano-engineering and material science to the pharmaceutical front. Currently, The research group is working on filling a number of patents that covers novel dosage form concepts.
3D Printing of solid and semi-solid dosage forms
Graphene based drug delivery systems
Natural and biodegradable coating system
Nano-coating technology of micro-scale structures
Scale-Up of advanced drug delivery systems
Improving In Vitro In Vivo Correlation (IVIVC) of poorly soluble drugs using flow-through cell systems.
Microencapsulation of nano-structured drug delivery systems