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Dr. Helene Thygesen

Lecturer

College of Health and Wellbeing

Brook Building, BB426

+44 (0) 1772 89 5539

hthygesen@uclan.ac.uk

Subject Areas: Health Informatics

Helene Thygesen is a lecturer/consultant in medical statistics, primarily for clinical trials. Helene is also a part of the research group Lancashire Clinical Trials Unit.

Full Profile

Qualifications:

Ph.D. Biostatistics (Amsterdam, 2006)

Research experience: Genomics, gene expression modelling, next generation sequencing, biochemical assays, in vitro experiments, clinical trial methodology, meta-analysis, psychometrics, cancer surgery, radiotherapy, immunology, biosecurity, population dynamics, compost management, food authenticity verification, sports statistics (foodball, tennis, baseball, cricket).

Research Activities

Use of immune markers in chemotherapy choice in gastric and penile cancer. Bayesian methods in interim analysis

Teaching Activities

Clinical trial methodology, StaXact intro, Critical reading of research papers, General introduction to medical statistics.

External Activities

Statistical consultant for Preston, Morecambe Bay and East Lancashire NHS trust, and St James Hospital (Leeds)

Publications

H Thygesen, T-L Su, J Whitehead, C Bowman. ESTIMATION STRATEGIES FOR REACTING TO THE IDENTIFICATION OF AN ASSOCIATION BETWEEN THE GENOME AND ADVERSE DRUG REACTIONS. Journal of Biopharmaceutial Statistics, January 2010.

H Thygesen and A H Zwinderman: Modelling the correlation between the activities of adjacent genes in drosophila BMC Bioinformatics 19 Jan 2005

H Thygesen and A H Zwinderman: Comparing transformation methods for DNA microarray data BMC Bioinformatics 17 Jun 2004

H Thygesen and A H Zwinderman: Modeling Sage data with a truncated gammaPoisson model BMC Bioinformatics, 20 Mar 2006

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Conferences

Will present at ISCB 2016, Birmingham

Projects

"Restrain Yourself"