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Dr Elaine Browne

Dr. Elaine Browne

Lecturer in Medical Sciences (Cell Biology & Genetics)

School of Medicine

Harrington Building, HA211

+44 (0) 1772 89 5947

ebrowne@uclan.ac.uk

Subject Areas: Biosciences, Cell Biology and Genetics

Dr Browne teaches Cell Biology and Immunology in the School of Medicine. She has 14 years of experience in the fields of cancer cell biology, radiobiology and immunology.

Full Profile

Dr Browne started her research career in the field of cancer cell biology assessing the efficacy of amino acid (arginine) deprivation as a means of anticancer therapy for her doctoral studies (University of Aberdeen and Cancer Treatments International, Zurich). She then moved to the University of St Andrews to work with Dr Peter Bryant on the bystander effect of radiation cancer therapy. After 3 years working in the field of radiobiology, she changed fields and began working with Dr Simon Powis on the way in which the MHC Class I molecule HLA-B27 misfolds in the inflammatory arthritic condition Ankylosing spondylitis.

Dr Browne joined the Medical School at UCLan in 2016

Qualifications
  • PhD. Pathology, University of Aberdeen, 2004
  • MPhil. Genetics, University of Aberdeen, 2001
  • BSc (Hons) Genetics, 2i, University of Aberdeen, 1994
Memberships
  • Genetics Society (1994-2014)
  • British Society for Cell Biology (2002-2014)
  • British Society for Immunology (2008-2014)
Teaching activities and responsibilities
  • Lecturer: MBBS, BDS, Medical Sciences.
  • Module lead: XY3120 Molecular Medicine and XY2010 Immunology

Publications

Guiliano, D.B., North, H., Panayoitou, E., Campbell, E.C., McHugh, K., Cooke, F.G., Silvestre, M., Bowness, P., Powis, S.J. and Antoniou, A.N. (2017) Polymorphisms in the F pocket of HLA-B27 subtypes strongly affects assembly, chaperone interactions, and heavy-chain misfolding. Arthritis and Rheumatism 69(3):610-621

Pulman, J., Nylk, J., Campbell, E.C., Gunn-Moore, F., Prystowsky, M.B. and Dholakia, K. (2016) Visualisation of podocyte substructure with Structured Illumination Microscopy (SIM): A new approach to nephrotic disease. Biomedical Optics Express 7(2):302-11

Chen, M., McReynolds, N., Campbell, E.C., Mazilu, M., Dholakia, K. and Powis, S.J. (2015) The use of wavelength Raman spectroscopy in label-free identification of T lymphocyte subsets, natural killer cells and dendritic cells. PLoS one 10(5):e0125158

Riches, A.C., Campbell, E.C., Borger, E. and Powis, S.J. (2014) Regulation of exosome release from mammary epithelial and breast cancer cells – a new regulatory pathway. European Journal of Cancer 50(5):1025-34

More publications