School of Medicine
Harrington Building, HA211
+44 (0) 1772 89 5947
Subject Areas: Biosciences, Cell Biology and Genetics
Dr Browne teaches Cell Biology and Immunology in the School of Medicine. She has 14 years of experience in the fields of cancer cell biology, radiobiology and immunology.
Dr Browne started her research career in the field of cancer cell biology assessing the efficacy of amino acid (arginine) deprivation as a means of anticancer therapy for her doctoral studies (University of Aberdeen and Cancer Treatments International, Zurich). She then moved to the University of St Andrews to work with Dr Peter Bryant on the bystander effect of radiation cancer therapy. After 3 years working in the field of radiobiology, she changed fields and began working with Dr Simon Powis on the way in which the MHC Class I molecule HLA-B27 misfolds in the inflammatory arthritic condition Ankylosing spondylitis.
Dr Browne joined the Medical School at UCLan in 2016
Guiliano, D.B., North, H., Panayoitou, E., Campbell, E.C., McHugh, K., Cooke, F.G., Silvestre, M., Bowness, P., Powis, S.J. and Antoniou, A.N. (2017) Polymorphisms in the F pocket of HLA-B27 subtypes strongly affects assembly, chaperone interactions, and heavy-chain misfolding. Arthritis and Rheumatism 69(3):610-621
Pulman, J., Nylk, J., Campbell, E.C., Gunn-Moore, F., Prystowsky, M.B. and Dholakia, K. (2016) Visualisation of podocyte substructure with Structured Illumination Microscopy (SIM): A new approach to nephrotic disease. Biomedical Optics Express 7(2):302-11
Chen, M., McReynolds, N., Campbell, E.C., Mazilu, M., Dholakia, K. and Powis, S.J. (2015) The use of wavelength Raman spectroscopy in label-free identification of T lymphocyte subsets, natural killer cells and dendritic cells. PLoS one 10(5):e0125158
Riches, A.C., Campbell, E.C., Borger, E. and Powis, S.J. (2014) Regulation of exosome release from mammary epithelial and breast cancer cells – a new regulatory pathway. European Journal of Cancer 50(5):1025-34