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Dr. Claire Mellor

Lecturer In Cell Biology

School of Forensic and Applied Sciences

Kirkham Building, KM105

+44 (0) 1772 89 4024

Cmellor3@uclan.ac.uk

Subject Areas: Allied Health, Biosciences, Pharmacy and Pharmacology

Claire is a Pharmacologist with a specific interest in understanding the mechanisms of drug toxicity in humans and the environment. Her research involves the use of computational toxicology methods in order to develop screening tools to aide in drug development and hazard assessment strategies.

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Claire completed her PhD in Pharmacology and Therapeutics as part of the Medical Research Centre at the University of Liverpool, where she studied toxicology of drugs. During her postdoctoral years she work as a computational toxicologist on many European wide projects as part of a multidisciplinary team. Her research has focused on both the human and environmental impacts of drugs and chemicals, evidenced by high impact publications in this field. Currently a Lecturer at UCLAN she aspires to instil passion for understanding toxicology into her students.

  • Ph.D. Pharmacology and Therapeutics, University of Liverpool, 2014
  • M.Res. Masters of Research, Drug Safety Science, University of Liverpool, 2010
  • B.Sc. Pharmacology and Therapeutics, University of Liverpool, 2009

Teaching activities and responsibilities 

Module contributions

  • FZ1601 – Introduction to Cell Biology
  • FZ1604 – Science and Society
  • FZ1014 – Biology for Forensic Scientists
  • FZ2604- Biology of health and Disease

Conferences

SEURAT-1 and COSMOS consortium meetings (Barcelona, 2014, 2015; Liverpool, 2015); International Environmental Omics conference (Liverpool, 2014); EDRISK meeting (Oslo, 2014); EUROTOX conference (Edinburgh, 2014); British Toxicology Society conference (Warwick, 2012).

Publications

Mellor, Claire, Nelms, Mark, Mark, Cronin, Judith, Madden and Steve, Enoch (2015) The development of an in silico profiler for mitochondrial toxicity. Chemical Research in Toxicology, 28 (10). pp. 1891-1902. ISSN 0893-228X

Mellor, Claire, Steinmetz, Fabian and Cronin, Mark (2016) Using Molecular Initiating Events to Develop a Structural Alert Based Screening Workflow for Nuclear Receptor Ligands Associated with Hepatic SteatosisChemical Research in Toxicology, 29 (2). pp. 203-212.

Mellor, Claire, Steinmetz, Fabian and Cronin, Mark (2016) The Identification of Nuclear Receptors Associated with Hepatic Steatosis to Develop and Extend Adverse Outcome Pathways. Critical Reviews in Toxicology, 46 (2). pp. 138-152. ISSN 1040-8444

Steinmetz, Fabian, Mellor, Claire, Meinl, Thorsten and Cronin, Mark (2015) Screening chemicals for receptor-mediated toxicological/ pharmacological endpoints: Using public data to build screening tools within KNIME.Molecular Informatics, 34 (2-3). 171 -178. ISSN 1868-1743