School of Forensic and Applied Sciences
Kirkham Building, KM105
+44 (0) 1772 89 4024
Subject Areas: Allied Health, Biosciences, Pharmacy and Pharmacology
Claire is a Pharmacologist with a specific interest in understanding the mechanisms of drug toxicity in humans and the environment. Her research involves the use of computational toxicology methods in order to develop screening tools to aide in drug development and hazard assessment strategies.
Claire completed her PhD in Pharmacology and Therapeutics as part of the Medical Research Centre at the University of Liverpool, where she studied toxicology of drugs. During her postdoctoral years she work as a computational toxicologist on many European wide projects as part of a multidisciplinary team. Her research has focused on both the human and environmental impacts of drugs and chemicals, evidenced by high impact publications in this field. Currently a Lecturer at UCLAN she aspires to instil passion for understanding toxicology into her students.
Teaching activities and responsibiltiies
SEURAT-1 and COSMOS consortium meetings (Barcelona, 2014, 2015; Liverpool, 2015); International Environmental Omics conference (Liverpool, 2014); EDRISK meeting (Oslo, 2014); EUROTOX conference (Edinburgh, 2014); British Toxicology Society conference (Warwick, 2012).
Mellor, Claire, Nelms, Mark, Mark, Cronin, Judith, Madden and Steve, Enoch (2015) The development of an in silico profiler for mitochondrial toxicity. Chemical Research in Toxicology, 28 (10). pp. 1891-1902. ISSN 0893-228X
Mellor, Claire, Steinmetz, Fabian and Cronin, Mark (2016) Using Molecular Initiating Events to Develop a Structural Alert Based Screening Workflow for Nuclear Receptor Ligands Associated with Hepatic Steatosis. Chemical Research in Toxicology, 29 (2). pp. 203-212.
Mellor, Claire, Steinmetz, Fabian and Cronin, Mark (2016) The Identification of Nuclear Receptors Associated with Hepatic Steatosis to Develop and Extend Adverse Outcome Pathways. Critical Reviews in Toxicology, 46 (2). pp. 138-152. ISSN 1040-8444
Steinmetz, Fabian, Mellor, Claire, Meinl, Thorsten and Cronin, Mark (2015) Screening chemicals for receptor-mediated toxicological/ pharmacological endpoints: Using public data to build screening tools within KNIME.Molecular Informatics, 34 (2-3). 171 -178. ISSN 1868-1743