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Model Biomembranes

Lyotropic lipid nanostructures and their hierarchically organized derivatives partly resemble biological configurations like plasma membrane, vesicles, Golgi apparatus, mitochondria and endoplasmic reticulum - ER (both smooth and rough) and also have important implications in their functioning.

Our group explores classical model membranes including Giant Unilamellar Vesicles (GUVs) and Free Standing Lipid Bilayers; however, we are more interested in exploiting other lipid nanostructures to mimic complex biomembranes architectures. 

Model Biomembranes

Related Publications

Pressure Effects on a Protein-Lipid Model Membrane

Kulkarni, C.V.*, O. Ces, R. H. Templer and J. M. Seddon* (2013) Soft Matter, 9 (28), 6525 - 6531.

Lipid Nanobilayers to Host Biological Nanopores for DNA Translocations

K. Göpfrich, C.V. Kulkarni, O.J. Pambos and U.F. Keyser* (2013) Langmuir 29: 355-364.

Lipid Crystallization: From Self Assembly to Hierarchical and Biological Ordering

Kulkarni, C.V.* (2012) Nanoscale, 4, (19): 5779-5791.

Evidence That Membrane Curvature Distorts the Tertiary Structure of Bacteriorhodopsin

Kulkarni, C.V., A. M. Seddon, O. Ces, and R. H. Templer.* (2010) Soft Matter, 6: 4339-4341.

Monoolein: Magic Lipid?

Kulkarni, C.V.*, W. Wachter, G. R. Iglesias, S. Engelskirchen and S. Ahualli (2011) Phys. Chem. Chem. Phys., 13 (8): 3004-3021.