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Lipid Phase Behaviour

By carefully selecting a set of lipid molecules one can engineer and thereby predict their behavior for self-assembling nanostructures.The classical phase behavior of various lipids can be further fine tuned by adding chemical and biological molecules and by modulating physicochemical triggers such as, temperature, pressure and shear.

Our projects involve basic understanding, calculation of molecular level parameters, fine tuning and application driven studies of lipid nanostructural behavior.

Related Publications

Biomolecules Altering the Lipid Molecular Shape in Model Non-Lamellar Membranes

Kulkarni,C.V*, Y. Patil-Sen, M.V. Kulkarni and A. Iglic. (2015) Biophys. J, 108 (2) Supplement 1 p544a.

Engineering Bicontinuous Cubic Structures at the Nanoscale– the Role of Chain Splay

Kulkarni, C.V., T. Y. Tang, A. M. Seddon, J.M. Seddon, O. Ces, and R. H. Templer.* (2010) Soft Matter, 6: 3191-3194

Nanostructural Studies on Monoelaidin-Water Systems at Low Temperatures

Kulkarni, C.V.* (2011) Langmuir, 27(19):11790-800

Monoolein: A Magic Lipid?

Kulkarni, C.V.*, W. Wachter, G. R. Iglesias, S. Engelskirchen and S. Ahualli. (2011) Phys. Chem. Chem. Phys., 13 (8): 3004-3021

Lipid Crystallization: From Self Assembly to Hierarchical and Biological Ordering

Kulkarni, C.V.* (2012) Nanoscale, 4, (19): 5779-5791.